Shaifali Bhalla, Ph.D.

The area of research in my laboratory is opioid tolerance and withdrawal. My research interests include exploring the signaling mechanisms involved in the pharmacological actions of opioid analgesics such as morphine and oxycodone. We are presently investigating the signaling pathways by which endothelin-A receptor antagonists enhance opioid analgesia and reverse analgesic tolerance. Our research is also focused on the role of endothelin-A and endothelin-B receptors in neuroadaptations in the brain during opioid withdrawal.